LHRH (4-10)

CAS No. 51776-33-1

LHRH (4-10)( ——— )

Catalog No. M41349 CAS No. 51776-33-1

LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    LHRH (4-10)
  • Note
    Research use only, not for human use.
  • Brief Description
    LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes.
  • Description
    LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes.
  • In Vitro
    The formation of LHRH 4-10, LHRH 7-10, and LHRH 6-10Co-incubation are inhibited by known enzyme inhibitors including Captopril (an ACE inhibitor), Thiorphan (an EP24.11 inhibitor), and Ethylenediaminetetraacetic acid (an EP24.15 inhibitor).LH-RH (4-10) inhibits the binding of 125I-labeled GnRH to monoclonal antibody P81662 with an IC50 value of 23 pM.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    51776-33-1
  • Formula Weight
    747.85
  • Molecular Formula
    C33H53N11O9
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yang X, et al. Enzymatic degradation of luteinizing hormone releasing hormone (LHRH)/D-Ala6-LHRH in lung pneumocytes. Pharm Res. 1998 Sep;15(9):1480-4.?
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